abstract：BACKGROUND:The hemibiotrophic fungus Moniliophthora perniciosa is the causal agent of Witches' broom, a disease of Theobroma cacao. The pathogen life cycle ends with the production of basidiocarps in dead tissues of the infected host. This structure generates millions of basidiospores that reinfect young tissues of the...

journal_title：BMC microbiology

authors： Pires AB,Gramacho KP,Silva DC,Góes-Neto A,Silva MM,Muniz-Sobrinho JS,Porto RF,Villela-Dias C,Brendel M,Cascardo JC,Pereira GA

更新日期：2009-08-04 00:00:00

abstract：BACKGROUND:The genus Arsenophonus is a group of symbiotic, mainly insect-associated bacteria with rapidly increasing number of records. It is known from a broad spectrum of hosts and symbiotic relationships varying from parasitic son-killers to coevolving mutualists.The present study extends the currently known diversi...

journal_title：BMC microbiology

authors： Nováková E,Hypsa V,Moran NA

更新日期：2009-07-20 00:00:00

abstract：BACKGROUND:Since 1994, Brucella strains have been isolated from a wide range of marine mammals. They are currently recognized as two new Brucella species, B. pinnipedialis for the pinniped isolates and B. ceti for the cetacean isolates in agreement with host preference and specific phenotypic and molecular markers. In ...

journal_title：BMC microbiology

authors： Maquart M,Le Flèche P,Foster G,Tryland M,Ramisse F,Djønne B,Al Dahouk S,Jacques I,Neubauer H,Walravens K,Godfroid J,Cloeckaert A,Vergnaud G

更新日期：2009-07-20 00:00:00

abstract：BACKGROUND:The KdpD/KdpE two-component system of Escherichia coli regulates expression of the kdpFABC operon encoding the high affinity K+ transport system KdpFABC. The input domain of KdpD comprises a domain that belongs to the family of universal stress proteins (Usp). It has been previously demonstrated that UspC bi...

journal_title：BMC microbiology

authors： Heermann R,Lippert ML,Jung K

更新日期：2009-07-09 00:00:00

abstract：BACKGROUND:Thiomonas strains are ubiquitous in arsenic-contaminated environments. Differences between Thiomonas strains in the way they have adapted and respond to arsenic have never been studied in detail. For this purpose, five Thiomonas strains, that are interesting in terms of arsenic metabolism were selected: T. a...

journal_title：BMC microbiology

authors： Bryan CG,Marchal M,Battaglia-Brunet F,Kugler V,Lemaitre-Guillier C,Lièvremont D,Bertin PN,Arsène-Ploetze F

更新日期：2009-06-23 00:00:00

abstract：BACKGROUND:In humans, the intestinal microbiota plays an important role in the maintenance of host health by providing energy, nutrients, and immunological protection. Applying current molecular methods is necessary to surmount the limitations of classical culturing techniques in order to obtain an accurate description...

journal_title：BMC microbiology

authors： Mariat D,Firmesse O,Levenez F,Guimarăes V,Sokol H,Doré J,Corthier G,Furet JP

更新日期：2009-06-09 00:00:00

abstract：BACKGROUND:Alpha-isopropylmalate synthase (alpha-IPMS) is the key enzyme that catalyzes the first committed step in the leucine biosynthetic pathway. The gene encoding alpha-IPMS in Mycobacterium tuberculosis, leuA, is polymorphic due to the insertion of 57-bp repeat units referred to as Variable Number of Tandem Repea...

journal_title：BMC microbiology

authors： Yindeeyoungyeon W,Likitvivatanavong S,Palittapongarnpim P

更新日期：2009-06-09 00:00:00

abstract：BACKGROUND:The kinetoplast DNA (kDNA) of trypanosomatids consists of an unusual arrangement of circular molecules catenated into a single network. The diameter of the isolated kDNA network is similar to that of the entire cell. However, within the kinetoplast matrix, the kDNA is highly condensed. Studies in Crithidia f...

journal_title：BMC microbiology

authors： Cavalcanti DP,Shimada MK,Probst CM,Souto-Padrón TC,de Souza W,Goldenberg S,Fragoso SP,Motta MC

更新日期：2009-06-04 00:00:00

abstract：BACKGROUND:Mosquitoes are intermediate hosts for numerous disease causing organisms. Vector control is one of the most investigated strategy for the suppression of mosquito-borne diseases. Anopheles stephensi is one of the vectors of malaria parasite Plasmodium vivax. The parasite undergoes major developmental and matu...

journal_title：BMC microbiology

authors： Rani A,Sharma A,Rajagopal R,Adak T,Bhatnagar RK

更新日期：2009-05-19 00:00:00

abstract：BACKGROUND:Thermotolerant Campylobacter is among the more prevalent bacterial pathogens that cause foodborne diseases. This study aimed at evaluating the occurrence of thermotolerant Campylobacter contamination in chicken carcasses and processing plant stations (chilling water, scalding water, defeathering machinery, e...

journal_title：BMC microbiology

authors： Figueroa G,Troncoso M,López C,Rivas P,Toro M

更新日期：2009-05-15 00:00:00

abstract：BACKGROUND:The 19 kDa lipoprotein of Mycobacterium tuberculosis (MTB) is an important target of the innate immune response. To investigate the effect of post-translation modification of this protein on innate recognition in the context of the whole bacillus, we derived a recombinant M. tuberculosis H37Rv that lacked th...

journal_title：BMC microbiology

authors： Wilkinson KA,Newton SM,Stewart GR,Martineau AR,Patel J,Sullivan SM,Herrmann JL,Neyrolles O,Young DB,Wilkinson RJ

更新日期：2009-05-14 00:00:00

abstract：BACKGROUND:The natural product Emodin demonstrates a wide range of pharmacological properties including anticancer, anti-inflammatory, antiproliferation, vasorelaxant and anti-H. pylori activities. Although its H. pylori inhibition was discovered, no acting target information against Emodin has been revealed to date. ...

journal_title：BMC microbiology

authors： Chen J,Zhang L,Zhang Y,Zhang H,Du J,Ding J,Guo Y,Jiang H,Shen X

更新日期：2009-05-12 00:00:00

abstract：BACKGROUND:Chlamydiae are obligate intracellular pathogens that possess a type III secretion system to deliver proteins into the host cell during infection. Small molecule inhibitors of type III secretion in Yersinia, termed INPs (Innate Pharmaceuticals AB) were reported to strongly inhibit Chlamydia growth in epitheli...

journal_title：BMC microbiology

authors： Muschiol S,Normark S,Henriques-Normark B,Subtil A

更新日期：2009-04-21 00:00:00

abstract：BACKGROUND:FliH is a protein involved in the export of components of the bacterial flagellum and we herein describe the presence of glycine-rich repeats in FliH of the form AxxxG(xxxG)mxxxA, where the value of m varies considerably in FliH proteins from different bacteria. While GxxxG and AxxxA patterns have previously...

journal_title：BMC microbiology

authors： Trost B,Moore SA

更新日期：2009-04-16 00:00:00

abstract：BACKGROUND:The human gastrointestinal (GI) tract microbiota is characterised by an abundance of uncultured bacteria most often assigned in phyla Firmicutes and Bacteroidetes. Diversity of this microbiota, even though approached with culture independent techniques in several studies, still requires more elucidation. The...

journal_title：BMC microbiology

authors： Krogius-Kurikka L,Kassinen A,Paulin L,Corander J,Mäkivuokko H,Tuimala J,Palva A

更新日期：2009-04-08 00:00:00

abstract：BACKGROUND:Brucellosis is an important zoonosis caused by the genus Brucella. In addition Brucella represents potential biological warfare agents due to the high contagious rates for humans and animals. Therefore, the strain typing epidemiological tool may be crucial for tracing back source of infection in outbreaks an...

journal_title：BMC microbiology

authors： De Santis R,Ciammaruconi A,Faggioni G,D'Amelio R,Marianelli C,Lista F

更新日期：2009-04-07 00:00:00

abstract：BACKGROUND:Trichomonas vaginalis is a human urogenital pathogen responsible for trichomonosis, the number-one, non-viral sexually transmitted disease (STD) worldwide, while T. tenax is a commensal of the human oral cavity, found particularly in patients with poor oral hygiene and advanced periodontal disease. The exten...

journal_title：BMC microbiology

authors： Kucknoor AS,Mundodi V,Alderete J

更新日期：2009-03-18 00:00:00

abstract：BACKGROUND:The last step in the maturation process of the large subunit of [NiFe]-hydrogenases is a proteolytic cleavage of the C-terminal by a hydrogenase specific protease. Contrary to other accessory proteins these hydrogenase proteases are believed to be specific whereby one type of hydrogenases specific protease o...

journal_title：BMC microbiology

authors： Devine E,Holmqvist M,Stensjö K,Lindblad P

更新日期：2009-03-11 00:00:00

abstract：:Protein secretion plays a central role in modulating the interactions of bacteria with their environments. This is particularly the case when symbiotic bacteria (whether pathogenic, commensal or mutualistic) are interacting with larger host organisms. In the case of Gram-negative bacteria, secretion requires transloca...

journal_title：BMC microbiology

authors： Tseng TT,Tyler BM,Setubal JC

更新日期：2009-02-19 00:00:00

abstract：BACKGROUND:Bacteria employ multiple mechanisms to control gene expression and react to their constantly changing environment. Bacterial growth in rich laboratory medium is a dynamic process in which bacteria utilize nutrients from simple to complex and change physical properties of the medium, as pH, during the process...

journal_title：BMC microbiology

authors： Sitkiewicz I,Musser JM

更新日期：2009-02-10 00:00:00

abstract：BACKGROUND:Microorganisms are a large and diverse form of life. Many of them live in association with large multicellular organisms, developing symbiotic relations with the host and some have even evolved to form obligate endosymbiosis. All Carpenter ants (genus Camponotus) studied hitherto harbour primary endosymbioti...

journal_title：BMC microbiology

authors： de Souza DJ,Bézier A,Depoix D,Drezen JM,Lenoir A

更新日期：2009-02-06 00:00:00

abstract：BACKGROUND:Dispersal from Candida albicans biofilms that colonize catheters is implicated as a primary factor in the link between contaminated catheters and life threatening blood stream infections (BSI). Appropriate in vitro C. albicans biofilm models are needed to probe factors that induce detachment events. RESULTS...

journal_title：BMC microbiology

authors： Sellam A,Al-Niemi T,McInnerney K,Brumfield S,Nantel A,Suci PA

更新日期：2009-02-02 00:00:00

abstract：BACKGROUND:Salmonella enterica serovar Typhimurium (Typhimurium) is an important pathogen that infects a broad range of hosts. In humans, Typhimurium causes a gastroenteritis characterized by vomiting, diarrhea, and abdominal pains. Typhimurium infection occurs mainly through the ingestion of contaminated food includin...

journal_title：BMC microbiology

authors： Dieye Y,Ameiss K,Mellata M,Curtiss R 3rd

更新日期：2009-01-06 00:00:00

abstract：BACKGROUND:A biofilm is a complex community of microorganisms that develop on surfaces in diverse environments. The thickness of the biofilm plays a crucial role in the physiology of the immobilized bacteria. The most cariogenic bacteria, mutans streptococci, are common inhabitants of a dental biofilm community. In thi...

journal_title：BMC microbiology

authors： Shemesh M,Tam A,Kott-Gutkowski M,Feldman M,Steinberg D

更新日期：2008-12-29 00:00:00

abstract：BACKGROUND:Emergence of drug resistant varieties of tuberculosis is posing a major threat to global tuberculosis eradication programmes. Although several approaches have been explored to counter resistance, there has been limited success due to a lack of understanding of how resistance emerges in bacteria upon drug tre...

journal_title：BMC microbiology

authors： Raman K,Chandra N

更新日期：2008-12-23 00:00:00

abstract：BACKGROUND:The cell tropism of Brucella abortus, a causative agent of brucellosis and facultative intracellular pathogen, in the placenta is thought to be a key event of infectious abortion, although the molecular mechanism for this is largely unknown. There is a higher degree of bacterial colonization in the placenta ...

journal_title：BMC microbiology

authors： Watanabe K,Tachibana M,Tanaka S,Furuoka H,Horiuchi M,Suzuki H,Watarai M

更新日期：2008-12-05 00:00:00

abstract：BACKGROUND:Iron is an essential nutrient but can be toxic at high intracellular concentrations and organisms have evolved tightly regulated mechanisms for iron uptake and homeostasis. Information on iron management mechanisms is available for organisms living at circumneutral pH. However, very little is known about how...

journal_title：BMC microbiology

authors： Osorio H,Martínez V,Nieto PA,Holmes DS,Quatrini R

更新日期：2008-11-24 00:00:00

abstract：BACKGROUND:The mce4 operon is one of the four homologues of mammalian cell entry (mce) operons of Mycobacterium tuberculosis. The mce4A (Rv3499c) gene within this operon is homologous to mce1A (Rv0169), that has a role in host cell invasion by M. tuberculosis. Our earlier reports show that mce4 operon is expressed duri...

journal_title：BMC microbiology

authors： Saini NK,Sharma M,Chandolia A,Pasricha R,Brahmachari V,Bose M

更新日期：2008-11-19 00:00:00

abstract：BACKGROUND:The Gifsy-I phage integrates into the Salmonella Typhimurium chromosome via an integrase mediated, site-specific recombination mechanism. Excision of the Gifsy-I phage requires three proteins, the Gifsy-I integrase (Int), the Gifsy-I excisionase (Xis) protein, and host encoded Integration Host Factor (IHF). ...

journal_title：BMC microbiology

authors： Flanigan A,Gardner J

更新日期：2008-11-17 00:00:00

abstract：BACKGROUND:Growing concerns about bacterial resistance to antibiotics have prompted the development of alternative therapies like those based on cationic antimicrobial peptides (APs). These compounds not only are bactericidal by themselves but also enhance the activity of antibiotics. Studies focused on the systematic ...

journal_title：BMC microbiology

authors： Sánchez-Gómez S,Lamata M,Leiva J,Blondelle SE,Jerala R,Andrä J,Brandenburg K,Lohner K,Moriyón I,Martínez-de-Tejada G

更新日期：2008-11-11 00:00:00

abstract：BACKGROUND:Chlamydia trachomatis, an obligate intracellular human pathogen, is the most prevalent bacterial sexually transmitted infection worldwide and a leading cause of preventable blindness. HtrA is a virulence and stress response periplasmic serine protease and molecular chaperone found in many bacteria. Recombina...

journal_title：BMC microbiology

authors： Huston WM,Theodoropoulos C,Mathews SA,Timms P

更新日期：2008-11-06 00:00:00

abstract：BACKGROUND:Streptococcus pneumoniae is a common respiratory pathogen and a major causative agent of respiratory infections, including otitis media (OM). Pneumococcal biofilms have been demonstrated on biopsies of the middle ear mucosa in children receiving tympanostomy tubes, supporting the hypothesis that chronic OM m...

journal_title：BMC microbiology

authors： Hall-Stoodley L,Nistico L,Sambanthamoorthy K,Dice B,Nguyen D,Mershon WJ,Johnson C,Hu FZ,Stoodley P,Ehrlich GD,Post JC

更新日期：2008-10-08 00:00:00

abstract：BACKGROUND:Bacterial and cellular genotyping is becoming increasingly important in the diagnosis of infectious diseases. However, difficulties in obtaining sufficient amount of bacterial and cellular DNA extracted from the same human biopsy specimens is often a limiting factor. In this study, total DNA (host and bacter...

journal_title：BMC microbiology

authors： Ryberg A,Borch K,Sun YQ,Monstein HJ

更新日期：2008-10-08 00:00:00

abstract：BACKGROUND:Mycoplasma pneumoniae has previously been characterized as a micro-organism that is genetically highly stable. In spite of this genetic stability, homologous DNA recombination has been hypothesized to lie at the basis of antigenic variation of the major surface protein, P1, of M. pneumoniae. In order to iden...

journal_title：BMC microbiology

authors： Sluijter M,Hoogenboezem T,Hartwig NG,Vink C

更新日期：2008-10-02 00:00:00

abstract：BACKGROUND:Predicting antibiotic resistance before it emerges at clinical settings constitutes a novel approach for preventing and fighting resistance of bacterial pathogens. To analyse the possibility that novel plasmid-encoded quinolone resistance determinants (Qnr) can emerge and disseminate among bacterial pathogen...

journal_title：BMC microbiology

authors： Sánchez MB,Hernández A,Rodríguez-Martínez JM,Martínez-Martínez L,Martínez JL

更新日期：2008-09-16 00:00:00

abstract：BACKGROUND:Salmonella enterica serotype Enteritidis (S. Enteritidis) is a zoonotic pathogen, which can be found in many sources including animals and the environment. However, little is known about the molecular relatedness among S. Enteritidis isolates from different sources. We have applied multiple-locus variable nu...

journal_title：BMC microbiology

authors： Cho S,Whittam TS,Boxrud DJ,Bartkus JM,Saeed AM

更新日期：2008-09-15 00:00:00

abstract：BACKGROUND:Propionibacterium acnes is a commensal of human skin but is also known to be involved in certain diseases, such as acne vulgaris and infections of orthopaedic implants. Treatment of these conditions is complicated by increased resistance to antibiotics and/or biofilm formation of P. acnes bacteria. P. acnes ...

journal_title：BMC microbiology

authors： Lood R,Mörgelin M,Holmberg A,Rasmussen M,Collin M

更新日期：2008-08-15 00:00:00

abstract：BACKGROUND:Following genital chlamydial infection, an early T helper type 1 (Th1)-associated immune response precedes the activation and recruitment of specific Th1 cells bearing distinct chemokine receptors, subsequently leading to the clearance of Chlamydia. We have shown that CCR5, a receptor for CCL5, is crucial fo...

journal_title：BMC microbiology

authors： Sakthivel SK,Singh UP,Singh S,Taub DD,Igietseme JU,Lillard JW Jr

更新日期：2008-08-13 00:00:00

abstract：BACKGROUND:A disrupted cell cycle progression of hepatocytes was reported in chronic hepatitis C virus (HCV) infection, which can contribute significantly in the associated pathogenesis. The present study aimed to further elaborate these disruptions by evaluating the expression of key cell cycle and apoptotic proteins ...

journal_title：BMC microbiology

authors： Sarfraz S,Hamid S,Siddiqui A,Hussain S,Pervez S,Alexander G

更新日期：2008-08-05 00:00:00

abstract：BACKGROUND:The increase in resistance to antibiotics among disease-causing bacteria necessitates the development of alternative antimicrobial approaches such as the use of light-activated antimicrobial agents (LAAAs). Light of an appropriate wavelength activates the LAAA to produce cytotoxic species which can then caus...

journal_title：BMC microbiology

authors： Omar GS,Wilson M,Nair SP

更新日期：2008-07-01 00:00:00